How body's good fat tissue communicates with brain Brown fat tissue, the body’s “good fat,” communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity, such as how much fat we have and how much fat we’ve lost, according to researchers.
Anti-obesity treatment in animal models developed A study has been conducted on obese mice and monkeys, using a drug which inhibits the activity of the PI3K enzyme. The body weight loss observed by researchers was exclusively due to a reduction in fat mass, and no toxic effects have been noted. The study also found an improvement in the symptoms of diabetes and hepatic steatosis (fatty liver disease), investigators report.
Why drug for type II diabetes makes people fat Medication used to treat patients with type II diabetes activates sensors on brain cells that increase hunger, causing people taking this drug to gain more body fat, according to researchers. The study describes a new way to affect hunger in the brain and helps to explain why people taking a class of drugs for type II diabetes gain more body fat.